Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models

Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection. Here we designed novel live attenuated ZIKV vaccine candida...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Li, Penghui, Ke, Xianliang, Wang, Ting, Tan, Zhongyuan, Luo, Dan, Miao, Yuanjiu, Sun, Jianhong, Zhang, Yuan, Liu, Yan, Hu, Qinxue, Xu, Fuqiang, Wang, Hanzhong, Zheng, Zhenhua
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096834/
https://ncbi.nlm.nih.gov/pubmed/29925661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00701-18
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