Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models

Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection. Here we designed novel live attenuated ZIKV vaccine candida...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Penghui, Ke, Xianliang, Wang, Ting, Tan, Zhongyuan, Luo, Dan, Miao, Yuanjiu, Sun, Jianhong, Zhang, Yuan, Liu, Yan, Hu, Qinxue, Xu, Fuqiang, Wang, Hanzhong, Zheng, Zhenhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096834/
https://ncbi.nlm.nih.gov/pubmed/29925661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00701-18
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