Influenza A Virus Attenuation by Codon Deoptimization of the NS Gene for Vaccine Development

Influenza viral infection represents a serious public health problem that causes contagious respiratory disease, which is most effectively prevented through vaccination to reduce transmission and future infection. The nonstructural (NS) gene of influenza A virus encodes an mRNA transcript that is al...

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Autori principali: Nogales, Aitor, Baker, Steven F., Ortiz-Riaño, Emilio, Dewhurst, Stephen, Topham, David J., Martínez-Sobrido, Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178899/
https://ncbi.nlm.nih.gov/pubmed/24965472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01565-14
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