Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models

Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection. Here we designed novel live attenuated ZIKV vaccine candida...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Li, Penghui, Ke, Xianliang, Wang, Ting, Tan, Zhongyuan, Luo, Dan, Miao, Yuanjiu, Sun, Jianhong, Zhang, Yuan, Liu, Yan, Hu, Qinxue, Xu, Fuqiang, Wang, Hanzhong, Zheng, Zhenhua
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096834/
https://ncbi.nlm.nih.gov/pubmed/29925661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00701-18
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