Docosahexaenoic acid inhibits zymogen activation by suppressing vacuolar ATPase activation in cerulein-stimulated pancreatic acinar cells

BACKGROUND: The premature activation of digestive enzyme zymogens within pancreatic acinar cells is an important early feature of acute pancreatitis. Supraphysiological concentrations of cholecystokinin (CCK) cause intrapancreatic zymogen activation and acute pancreatitis. Stimulation of vacuolar AT...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Nutr
Päätekijät: Park, Yeeun, Ku, Leeyeon, Lim, Joo Weon, Kim, Hyeyoung
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092610/
https://ncbi.nlm.nih.gov/pubmed/32293245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-020-00664-2
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