Docosahexaenoic acid inhibits zymogen activation by suppressing vacuolar ATPase activation in cerulein-stimulated pancreatic acinar cells

BACKGROUND: The premature activation of digestive enzyme zymogens within pancreatic acinar cells is an important early feature of acute pancreatitis. Supraphysiological concentrations of cholecystokinin (CCK) cause intrapancreatic zymogen activation and acute pancreatitis. Stimulation of vacuolar AT...

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Detaylı Bibliyografya
Yayımlandı:Genes Nutr
Asıl Yazarlar: Park, Yeeun, Ku, Leeyeon, Lim, Joo Weon, Kim, Hyeyoung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092610/
https://ncbi.nlm.nih.gov/pubmed/32293245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-020-00664-2
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