RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors

BACKGROUND: Invasive urothelial carcinoma (iUC) is highly similar between dogs and humans in terms of pathologic presentation, molecular subtypes, response to treatment and age at onset. Thus, the dog is an established and relevant model for testing and development of targeted drugs benefiting both...

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Publicado en:BMC Cancer
Main Authors: Parker, Heidi G., Dhawan, Deepika, Harris, Alex C., Ramos-Vara, Jose A., Davis, Brian W., Knapp, Deborah W., Ostrander, Elaine A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092566/
https://ncbi.nlm.nih.gov/pubmed/32209086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06737-0
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