Homologous Mutation to Human BRAF V600E is Common in Naturally Occurring Canine Bladder Cancer—Evidence for a Relevant Model System and Urine-based Diagnostic Test

Targeted cancer therapies offer great clinical promise, but treatment resistance is common, and basic research aimed at overcoming this challenge is limited by reduced genomic and biological complexity in artificially induced rodent tumors compared to their human counterparts. Animal models that mor...

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Detalles Bibliográficos
Publicado en:Mol Cancer Res
Main Authors: Decker, Brennan, Parker, Heidi G., Dhawan, Deepika, Kwon, Erika M., Karlins, Eric, Davis, Brian W., Ramos-Vara, José A., Bonney, Patty L., McNiel, Elizabeth A., Knapp, Deborah W., Ostrander, Elaine A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470794/
https://ncbi.nlm.nih.gov/pubmed/25767210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0689
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