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Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test

BACKGROUND: The standard Ames test strains owe their high sensitivity to chemical and physical mutagens to the episomal Y-family DNA polymerase RI encoded by the mucAB operon. The S. typhimurium test strains carry also another related samAB operon on a 60-kDa cryptic plasmid. In contrast to the chro...

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Bibliografiske detaljer
Udgivet i:Genes Environ
Main Authors: Grúz, Petr, Shimizu, Masatomi, Sugiyama, Kei-ichi, Yamada, Masami, Honma, Masamitsu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092418/
https://ncbi.nlm.nih.gov/pubmed/32211083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-020-00154-2
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