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Involvement of Y-Family DNA Polymerases in Mutagenesis Caused by Oxidized Nucleotides in Escherichia coli

Escherichia coli DNA polymerase IV incorporated 2-hydroxy-dATP opposite template guanine or thymine and 8-hydroxy-dGTP exclusively opposite adenine in vitro. Mutator phenotypes in sod/fur strains were substantially diminished by deletion of dinB and/or umuDC. DNA polymerases IV and V may be involved...

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主要な著者: Yamada, Masami, Nunoshiba, Tatsuo, Shimizu, Masatomi, Gruz, Petr, Kamiya, Hiroyuki, Harashima, Hideyoshi, Nohmi, Takehiko
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482991/
https://ncbi.nlm.nih.gov/pubmed/16788208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00281-06
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