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Conformational States Control Lck Switching between Free and Confined Diffusion Modes in T Cells
T cell receptor phosphorylation by Lck is an essential step in T cell activation. It is known that the conformational states of Lck control enzymatic activity; however, the underlying principles of how Lck finds its substrate over the plasma membrane remain elusive. Here, single-particle tracking is...
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| Publicado en: | Biophys J |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7091564/ https://ncbi.nlm.nih.gov/pubmed/32097620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.01.041 |
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