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Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
The occurrence of repetitive genomic changes that provide a selective growth advantage in pluripotent stem cells is of concern for their clinical application. However, the effect of different culture conditions on the underlying mutation rate is unknown. Here we show that the mutation rate in two hu...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7089967/ https://ncbi.nlm.nih.gov/pubmed/32251294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15271-3 |
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