Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease

We performed post-mortem studies on two patients with advanced Parkinson’s disease 8 and10 years following AAV2-neurturin (CERE120) gene therapy, the longest post-mortem trophic factor gene therapy cases reported to date. CERE120 was delivered to the putamen bilaterally in one case (10 years post-su...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Brain
Main Authors: Chu, Yaping, Bartus, Raymond T, Manfredsson, Fredric P, Olanow, C Warren, Kordower, Jeffrey H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089653/
https://ncbi.nlm.nih.gov/pubmed/32203581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa020
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