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Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

The pace of nigrostriatal degeneration, both with regards to striatal denervation and loss of melanin and tyrosine hydroxylase-positive neurons, is poorly understood especially early in the Parkinson’s disease process. This study investigated the extent of nigrostriatal degeneration in patients with...

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Detalhes bibliográficos
Main Authors: Kordower, Jeffrey H., Olanow, C. Warren, Dodiya, Hemraj B., Chu, Yaping, Beach, Thomas G., Adler, Charles H., Halliday, Glenda M., Bartus, Raymond T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722357/
https://ncbi.nlm.nih.gov/pubmed/23884810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt192
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