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Tunable pH-Sensitive 2-Carboxybenzyl Phosphoramidate Cleavable Linkers
We previously described a pH-sensitive phosphoramidate linker scaffold that can be tuned to release amine-containing drugs at various pH values. In these previous studies it was determined that the tunability of this linker was dependent upon the proximity of an acidic group (e.g., carboxylic acid o...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7089582/ https://ncbi.nlm.nih.gov/pubmed/32205898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2020.151650 |
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