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Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor
[Image: see text] Amylin is coexpressed with insulin in pancreatic islet β-cells and has potent effects on gastric emptying and food intake. The effect of amylin on satiation has been postulated to involve AMY(3) receptors (AMY(3)R) that are heteromers of the calcitonin receptor (CTR) and receptor a...
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| 出版年: | ACS Pharmacol Transl Sci |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American
Chemical Society
2019
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7088965/ https://ncbi.nlm.nih.gov/pubmed/32219220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00010 |
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