The Molecular Control of Calcitonin Receptor Signaling

[Image: see text] The calcitonin receptor (CTR) is a class B G protein-coupled receptor (GPCR) that responds to the peptide hormone calcitonin (CT). CTs are clinically approved for the treatment of bone diseases. We previously reported a 4.1 Å structure of the activated CTR bound to salmon CT (sCT)...

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Udgivet i:ACS Pharmacol Transl Sci
Main Authors: dal Maso, Emma, Glukhova, Alisa, Zhu, Yue, Garcia-Nafria, Javier, Tate, Christopher G., Atanasio, Silvia, Reynolds, Christopher A., Ramírez-Aportela, Erney, Carazo, Jose-Maria, Hick, Caroline A., Furness, Sebastian G. B., Hay, Debbie L., Liang, Yi-Lynn, Miller, Laurence J., Christopoulos, Arthur, Wang, Ming-Wei, Wootten, Denise, Sexton, Patrick M.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088896/
https://ncbi.nlm.nih.gov/pubmed/32219215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00056
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