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Structural Insight into G Protein-Coupled Receptor Signaling Efficacy and Bias between Gs and β-Arrestin
[Image: see text] G protein-coupled receptors (GPCRs) form the largest family of membrane proteins involved in signal transduction. Because of their ability to regulate a wide range of cellular responses and their dysregulation being associated with many diseases, GPCRs remain a key therapeutic targ...
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| Pubblicato in: | ACS Pharmacol Transl Sci |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2019
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7088954/ https://ncbi.nlm.nih.gov/pubmed/32259053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00012 |
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