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Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling
Seven-transmembrane receptors (7TMRs) are involved in nearly all aspects of chemical communications and represent major drug targets. 7TMRs transmit their signals not only via heterotrimeric G proteins but also through β-arrestins, whose recruitment to the activated receptor is regulated by G protei...
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| 主要な著者: | , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397412/ https://ncbi.nlm.nih.gov/pubmed/22735336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.22 |
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