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Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor

Signaling through β-arrestins is a recently appreciated mechanism used by seven-transmembrane receptors. Because G protein-coupled receptor kinase (GRK) phosphorylation of such receptors is generally a prerequisite for β-arrestin binding, we studied the roles of different GRKs in promoting β-arresti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ren, Xiu-Rong, Reiter, Eric, Ahn, Seungkirl, Kim, Jihee, Chen, Wei, Lefkowitz, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC547876/
https://ncbi.nlm.nih.gov/pubmed/15671180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409534102
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