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Beyond Glucagon-like Peptide-1: Is G-Protein Coupled Receptor Polypharmacology the Path Forward to Treating Metabolic Diseases?
[Image: see text] The glucagon-like peptide-1 receptor (GLP-1R) is a class B G-protein coupled receptor (GPCR) that has proven to be an effective target for developing medicines that treat type 2 diabetes mellitus (T2DM). GLP-1R agonists improve T2DM by enhancing glucose-stimulated insulin secretion...
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| Publicado en: | ACS Pharmacol Transl Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American
Chemical Society
2018
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7088942/ https://ncbi.nlm.nih.gov/pubmed/32219200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00009 |
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