GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function

Por Lin, Hua V., Wang, Jingru, Wang, Jie, Li, Weiji, Wang, Xuesong, Alston, James T., Thomas, Melissa K., Briere, Daniel A., Syed, Samreen K., Efanov, Alexander M.
Publicado no Mol Metab (2018)

Novel Small Molecule Agonist of TGR5 Possesses Anti-Diabetic Effects but Causes Gallbladder Filling in Mice

Por Briere, Daniel A., Ruan, Xiaoping, Cheng, Christine C., Siesky, Angela M., Fitch, Thomas E., Dominguez, Carmen, Sanfeliciano, Sonia Gutierrez, Montero, Carlos, Suen, Chen S., Xu, Yanping, Coskun, Tamer, Michael, M. Dodson
Publicado no PLoS One (2015)

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

Por Coskun, Tamer, Sloop, Kyle W., Loghin, Corina, Alsina-Fernandez, Jorge, Urva, Shweta, Bokvist, Krister B., Cui, Xuewei, Briere, Daniel A., Cabrera, Over, Roell, William C., Kuchibhotla, Uma, Moyers, Julie S., Benson, Charles T., Gimeno, Ruth E., D'Alessio, David A., Haupt, Axel
Publicado no Mol Metab (2018)