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Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor

The therapeutic success of peptide glucagon-like peptide-1 (GLP-1) receptor agonists for the treatment of type 2 diabetes mellitus has inspired discovery efforts aimed at developing orally available small molecule GLP-1 receptor agonists. Although the GLP-1 receptor is a member of the structurally c...

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Autors principals: Willard, Francis S., Bueno, Ana B., Sloop, Kyle W.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352573/
https://ncbi.nlm.nih.gov/pubmed/22611375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/709893
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