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Targeting Functional Activity of AKT Has Efficacy against Aggressive Neuroblastoma
[Image: see text] MYCN-amplified neuroblastoma is one of the deadliest forms of childhood cancer and remains a significant clinical challenge. Direct pharmacological inhibition of MYCN is not currently achievable. One strategy could be to target the AKT/GSK3β pathway, which directly regulates the st...
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| Publicado no: | ACS Pharmacol Transl Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7088937/ https://ncbi.nlm.nih.gov/pubmed/32259094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00085 |
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