The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance

We previously identified the transcription factor ZNF217 (human) / Zfp217 (mouse) as an oncogene and prognostic indicator of reduced survival, increased metastasis, and reduced response to therapy in breast cancer patients. Here we investigated the role of Zfp217 in chemotherapy resistance. Preclini...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Suarez, Christopher D., Wu, Junmin, Badve, Sunil S., Sparano, Joseph A., Kaliney, William, Littlepage, Laurie E.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752462/
https://ncbi.nlm.nih.gov/pubmed/29312549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19308
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