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The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance

We previously identified the transcription factor ZNF217 (human) / Zfp217 (mouse) as an oncogene and prognostic indicator of reduced survival, increased metastasis, and reduced response to therapy in breast cancer patients. Here we investigated the role of Zfp217 in chemotherapy resistance. Preclini...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Suarez, Christopher D., Wu, Junmin, Badve, Sunil S., Sparano, Joseph A., Kaliney, William, Littlepage, Laurie E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752462/
https://ncbi.nlm.nih.gov/pubmed/29312549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19308
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