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T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma

The cancer-testis antigen NY-ESO-1 is expressed by many solid tumors and has limited expression by mature somatic tissues, making it a highly attractive target for tumor immunotherapy. Targeting NY-ESO-1 using engineered T cells has demonstrated clinical efficacy in the treatment of some adult tumor...

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Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Singh, Nathan, Kulikovskaya, Irina, Barrett, David M., Binder-Scholl, Gwendolyn, Jakobsen, Bent, Martinez, Daniel, Pawel, Bruce, June, Carl H., Kalos, Michael D., Grupp, Stephan A.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760344/
https://ncbi.nlm.nih.gov/pubmed/26942053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1040216
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