Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice

[Image: see text] Oxycodone is a potent medicinal opioid analgesic to treat pain. It is also addictive and a main cause for the current opioid crisis. At present, the impact of oxycodone on coordinated brain network activities, and contribution of the mu opioid receptor (MOR) to these effects, is un...

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Détails bibliographiques
Publié dans:ACS Pharmacol Transl Sci
Auteurs principaux: Nasseef, Md Taufiq, Singh, Jai Puneet, Ehrlich, Aliza T., McNicholas, Michael, Park, Da Woon, Ma, Weiya, Kulkarni, Praveen, Kieffer, Brigitte L., Darcq, Emmanuel
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2019
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088903/
https://ncbi.nlm.nih.gov/pubmed/32259060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00021
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