TouchScreen-based phenotyping: altered stimulus/reward association and lower perseveration to gain a reward in mu opioid receptor knockout mice

While the contribution of Mu Opioid Receptors (MORs) to hedonic aspects of reward processing is well-established, the notion that these receptors may also regulate motivation to gain a reward, and possibly other related cognitive dimensions, has been less investigated. The prefrontal cortex (PFC) is...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Boulos, Laura-Joy, Nasseef, Md. Taufiq, McNicholas, Michael, Mechling, Anna, Harsan, Laura Adela, Darcq, Emmanuel, Ben Hamida, Sami, Kieffer, Brigitte Lina
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411729/
https://ncbi.nlm.nih.gov/pubmed/30858487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40622-6
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