Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

Connectome genetics seeks to uncover how genetic factors shape brain functional connectivity; however, the causal impact of a single gene’s activity on whole-brain networks remains unknown. We tested whether the sole targeted deletion of the mu opioid receptor gene (Oprm1) alters the brain connectom...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Mechling, Anna E., Arefin, Tanzil, Lee, Hsu-Lei, Bienert, Thomas, Reisert, Marco, Ben Hamida, Sami, Darcq, Emmanuel, Ehrlich, Aliza, Gaveriaux-Ruff, Claire, Parent, Maxime J., Rosa-Neto, Pedro, Hennig, Jürgen, von Elverfeldt, Dominik, Kieffer, Brigitte Lina, Harsan, Laura-Adela
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2016
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068324/
https://ncbi.nlm.nih.gov/pubmed/27671662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601640113
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