Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice

[Image: see text] Oxycodone is a potent medicinal opioid analgesic to treat pain. It is also addictive and a main cause for the current opioid crisis. At present, the impact of oxycodone on coordinated brain network activities, and contribution of the mu opioid receptor (MOR) to these effects, is un...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Nasseef, Md Taufiq, Singh, Jai Puneet, Ehrlich, Aliza T., McNicholas, Michael, Park, Da Woon, Ma, Weiya, Kulkarni, Praveen, Kieffer, Brigitte L., Darcq, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088903/
https://ncbi.nlm.nih.gov/pubmed/32259060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00021
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