Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice

[Image: see text] Oxycodone is a potent medicinal opioid analgesic to treat pain. It is also addictive and a main cause for the current opioid crisis. At present, the impact of oxycodone on coordinated brain network activities, and contribution of the mu opioid receptor (MOR) to these effects, is un...

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Publicado en:ACS Pharmacol Transl Sci
Autores principales: Nasseef, Md Taufiq, Singh, Jai Puneet, Ehrlich, Aliza T., McNicholas, Michael, Park, Da Woon, Ma, Weiya, Kulkarni, Praveen, Kieffer, Brigitte L., Darcq, Emmanuel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2019
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088903/
https://ncbi.nlm.nih.gov/pubmed/32259060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00021
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