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Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease

INTRODUCTION: Possession of the apolipoprotein E (APO E) ε4 allele advances amyloid β (Aβ) deposition and symptomatic onset of Alzheimer's disease (AD), whereas its effect on the rate of cognitive decline remained controversial. We examined the effects of APOE ε4 allele on cognition in biomarke...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (N Y)
Main Authors: Suzuki, Kazushi, Hirakawa, Akihiro, Ihara, Ryoko, Iwata, Atsushi, Ishii, Kenji, Ikeuchi, Takeshi, Sun, Chung‐Kai, Donohue, Michael, Iwatsubo, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087431/
https://ncbi.nlm.nih.gov/pubmed/32211510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/trc2.12007
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