Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease

INTRODUCTION: Possession of the apolipoprotein E (APO E) ε4 allele advances amyloid β (Aβ) deposition and symptomatic onset of Alzheimer's disease (AD), whereas its effect on the rate of cognitive decline remained controversial. We examined the effects of APOE ε4 allele on cognition in biomarke...

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Vydáno v:Alzheimers Dement (N Y)
Hlavní autoři: Suzuki, Kazushi, Hirakawa, Akihiro, Ihara, Ryoko, Iwata, Atsushi, Ishii, Kenji, Ikeuchi, Takeshi, Sun, Chung‐Kai, Donohue, Michael, Iwatsubo, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087431/
https://ncbi.nlm.nih.gov/pubmed/32211510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/trc2.12007
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