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Innate Inflammation Drives NK Cell Activation to Impair Treg Activity
IL-12 and IL-18 synergize to promote T(H)1 responses and have been implicated as accelerators of autoimmune pathogenesis in type 1 diabetes (T1D). We investigated the influence of these cytokines on immune cells involved in human T1D progression: natural killer (NK) cells, regulatory T cells (Tregs)...
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| Veröffentlicht in: | J Autoimmun |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086400/ https://ncbi.nlm.nih.gov/pubmed/32035746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2020.102417 |
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