A New Humanized Mouse Model Mimics Humans in Lacking α-Gal Epitopes and Secreting Anti-Gal Antibodies

Mice have been used as accepted tools for investigating complex human diseases and new drug therapies because of their shared genetics and anatomical characteristics with humans. However, the tissues in mice are different from humans in that human cells have a natural mutation in the α1,3 galactosyl...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Saleh, Fayez M., Chandra, Partha K., Lin, Dong, Robinson, James E., Izadpanah, Reza, Mondal, Debasis, Bollensdorff, Christian, Alt, Eckhard U., Zhu, Quan, Marasco, Wayne A., Braun, Stephen E., Abdel-Motal, Ussama M.
Format: Artigo
Idioma:Inglês
Publicat: AAI 2020
Matèries:
Novel Immunological Methods
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086386/
https://ncbi.nlm.nih.gov/pubmed/32144163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901385
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