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Immunogenicity of Influenza Virus Vaccine Is Increased by Anti-Gal-Mediated Targeting to Antigen-Presenting Cells

This study describes a method for increasing the immunogenicity of influenza virus vaccines by exploiting the natural anti-Gal antibody to effectively target vaccines to antigen-presenting cells (APC). This method is based on enzymatic engineering of carbohydrate chains on virus envelope hemagglutin...

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Detalhes bibliográficos
Main Authors: Abdel-Motal, Ussama M., Guay, Heath M., Wigglesworth, Kim, Welsh, Raymond M., Galili, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951452/
https://ncbi.nlm.nih.gov/pubmed/17609270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00647-07
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