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Increased Immunogenicity of Human Immunodeficiency Virus gp120 Engineered To Express Galα1-3Galβ1-4GlcNAc-R Epitopes

The glycan shield comprised of multiple carbohydrate chains on the human immunodeficiency virus (HIV) envelope glycoprotein gp120 helps the virus to evade neutralizing antibodies. The present study describes a novel method for increasing immunogenicity of gp120 vaccine by enzymatic replacement of si...

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Detalhes bibliográficos
Main Authors: Abdel-Motal, Ussama, Wang, Shixia, Lu, Shan, Wigglesworth, Kim, Galili, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489031/
https://ncbi.nlm.nih.gov/pubmed/16809300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00310-06
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