Synthesis of Galα(1,3)Galβ(1,4)GlcNAcα-, Galβ(1,4)GlcNAcα- and GlcNAc-containing neoglycoproteins and their immunological evaluation in the context of Chagas disease

The protozoan parasite, Trypanosoma cruzi, the etiologic agent of Chagas disease (ChD), has a cell surface covered by immunogenic glycoconjugates. One of the immunodominant glycotopes, the trisaccharide Galα(1,3)Galβ(1,4)GlcNAcα, is expressed on glycosylphosphatidylinositol-anchored mucins of the in...

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Détails bibliographiques
Publié dans:Glycobiology
Auteurs principaux: Schocker, Nathaniel S, Portillo, Susana, Brito, Carlos R N, Marques, Alexandre F, Almeida, Igor C, Michael, Katja
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
ORIGINAL ARTICLES
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672149/
https://ncbi.nlm.nih.gov/pubmed/26384953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwv081
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