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Chemical Synthesis of Human Milk Oligosaccharides: Lacto‑N‑hexaose Galβ1→3GlcNAcβ1→3 [Galβ1→4GlcNAcβ1→6] Galβ1→4Glc

The first synthesis of lacto-N-hexaose (LNH) has been completed using a convergent strategy. The donor–acceptor protecting–leaving group combinations were found to be of paramount significance for achieving successful glycosylations and minimizing side reactions. Lacto-N-tetraose, another common hum...

詳細記述

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書誌詳細
出版年:J Org Chem
主要な著者: Bandara, Mithila D., Stine, Keith J., Demchenko, Alexei V.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114087/
https://ncbi.nlm.nih.gov/pubmed/31749363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02701
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