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Chemical Synthesis of Human Milk Oligosaccharides: Lacto‑N‑hexaose Galβ1→3GlcNAcβ1→3 [Galβ1→4GlcNAcβ1→6] Galβ1→4Glc
The first synthesis of lacto-N-hexaose (LNH) has been completed using a convergent strategy. The donor–acceptor protecting–leaving group combinations were found to be of paramount significance for achieving successful glycosylations and minimizing side reactions. Lacto-N-tetraose, another common hum...
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| Publicado no: | J Org Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8114087/ https://ncbi.nlm.nih.gov/pubmed/31749363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02701 |
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