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Targeting REV-ERBα for therapeutic purposes: promises and challenges
REV-ERBα (NR1D1) is a circadian clock component that functions as a transcriptional repressor. Due to its role in direct modulation of metabolic genes, REV-ERBα is regarded as an integrator of cell metabolism with circadian clock. Accordingly, REV-ERBα is first proposed as a drug target for treating...
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| 出版年: | Theranostics |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Ivyspring International Publisher
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086371/ https://ncbi.nlm.nih.gov/pubmed/32226546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43834 |
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