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Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function

The nuclear receptor Rev-erbα regulates circadian rhythm and metabolism, but its effects are modest and it has been considered to be a secondary regulator of the cell-autonomous clock. Here we report that depletion of Rev-erbα together with closely related Rev-erbβ has dramatic effects on the cell-a...

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Detalhes bibliográficos
Main Authors: Bugge, Anne, Feng, Dan, Everett, Logan J., Briggs, Erika R., Mullican, Shannon E., Wang, Fenfen, Jager, Jennifer, Lazar, Mitchell A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323877/
https://ncbi.nlm.nih.gov/pubmed/22474260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.186858.112
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