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Targeting REV-ERBα for therapeutic purposes: promises and challenges
REV-ERBα (NR1D1) is a circadian clock component that functions as a transcriptional repressor. Due to its role in direct modulation of metabolic genes, REV-ERBα is regarded as an integrator of cell metabolism with circadian clock. Accordingly, REV-ERBα is first proposed as a drug target for treating...
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| Publicat a: | Theranostics |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Ivyspring International Publisher
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086371/ https://ncbi.nlm.nih.gov/pubmed/32226546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43834 |
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