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Blockade of the mTOR signaling pathway with rapamycin ameliorates aristolochic acid nephropathy
Chronic aristolochic acid nephropathy (CAAN) is characterized by widespread apoptosis and interstitial fibrosis, which severely impairs kidney function. mTOR is crucial for cell proliferation and protein synthesis. In the present study, the therapeutic effects of blockade of mTOR activity by rapamyc...
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| Опубликовано в: : | Exp Ther Med |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086201/ https://ncbi.nlm.nih.gov/pubmed/32256773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8550 |
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