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Blockade of the mTOR signaling pathway with rapamycin ameliorates aristolochic acid nephropathy
Chronic aristolochic acid nephropathy (CAAN) is characterized by widespread apoptosis and interstitial fibrosis, which severely impairs kidney function. mTOR is crucial for cell proliferation and protein synthesis. In the present study, the therapeutic effects of blockade of mTOR activity by rapamyc...
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| Published in: | Exp Ther Med |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
D.A. Spandidos
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086201/ https://ncbi.nlm.nih.gov/pubmed/32256773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8550 |
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