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Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways

Melanoma is the deadliest form of skin cancer, and its incidence has continuously increased over the past 20 years. Therefore, the discovery of a novel targeted therapeutic strategy for melanoma is urgently needed. In our study, MTT-based cell proliferation assay, cell cycle, and apoptosis assays th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zhao, Qian, Zhu, Hong-Ping, Xie, Xin, Mao, Qing, Liu, Yan-Qing, He, Xiang-Hong, Peng, Cheng, Jiang, Qing-Lin, Huang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084941/
https://ncbi.nlm.nih.gov/pubmed/32156008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051845
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