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Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing’s Disease

PURPOSE: To investigate the role of heat-shock protein Hsp90 in adrenocorticotropic hormone (ACTH)-secreting cells, and to explore the potential clinical application of an inhibitor of Hsp90, 17-N-allylamino-17-demethoxygeldanamycin(17-AAG) in corticotropinomas [also known as “Cushing’s disease” (CD...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Shen, Yue, Ji, Chenxing, Jian, Xuemin, Zhou, Juan, Zhang, Qilin, Qiao, Nidan, Zhang, Yichao, Shou, Xuefei, Zhou, Xiang, Ma, Zengyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848029/
https://ncbi.nlm.nih.gov/pubmed/33537004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.601984
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