Focused Ultrasound Pre-Conditioning for Augmented Nanoparticle Penetration and Efficacy in the Central Nervous System

Microbubble activation with focused ultrasound (FUS) facilitates the non-invasive and spatially-targeted delivery of systemically administered therapeutics across the blood-brain barrier (BBB). FUS also augments the penetration of nanoscale therapeutics through brain tissue; however, this secondary...

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Publicat a:Small
Autors principals: Mead, Brian P., Curley, Colleen T., Kim, Namho, Negron, Karina, Garrison, William J., Song, Ji, Rao, Divya, Miller, G. Wilson, Mandell, James W., Purow, Benjamin W., Suk, Jung Soo, Hanes, Justin, Price, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084172/
https://ncbi.nlm.nih.gov/pubmed/31642183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201903460
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