Focused Ultrasound Pre-Conditioning for Augmented Nanoparticle Penetration and Efficacy in the Central Nervous System

Microbubble activation with focused ultrasound (FUS) facilitates the non-invasive and spatially-targeted delivery of systemically administered therapeutics across the blood-brain barrier (BBB). FUS also augments the penetration of nanoscale therapeutics through brain tissue; however, this secondary...

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Detalhes bibliográficos
Publicado no:Small
Main Authors: Mead, Brian P., Curley, Colleen T., Kim, Namho, Negron, Karina, Garrison, William J., Song, Ji, Rao, Divya, Miller, G. Wilson, Mandell, James W., Purow, Benjamin W., Suk, Jung Soo, Hanes, Justin, Price, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084172/
https://ncbi.nlm.nih.gov/pubmed/31642183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201903460
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