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Novel Focused Ultrasound Gene Therapy Approach Noninvasively Restores Dopaminergic Neuron Function in a Rat Parkinson’s Disease Model

Therapies capable of decelerating, or perhaps even halting, neurodegeneration in Parkinson’s disease (PD) remain elusive. Clinical trials of PD gene therapy testing the delivery of neurotrophic factors, such as the glial cell-line derived neurotrophic factor (GDNF), have been largely ineffective due...

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Bibliografiske detaljer
Udgivet i:Nano Lett
Main Authors: Mead, Brian P., Kim, Namho, Miller, G. Wilson, Hodges, David, Mastorakos, Panagiotis, Klibanov, Alexander L., Mandell, James W., Hirsh, Jay, Suk, Jung Soo, Hanes, Justin, Price, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539956/
https://ncbi.nlm.nih.gov/pubmed/28511006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.7b00616
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