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RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription
All organisms—bacteria, archaea, and eukaryotes—have a transcription initiation factor that contains a structural module that binds within the RNA polymerase (RNAP) active-center cleft and interacts with template-strand single-stranded DNA (ssDNA) in the immediate vicinity of the RNAP active center....
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7084136/ https://ncbi.nlm.nih.gov/pubmed/32127479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920747117 |
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