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X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway

Reiterative transcription is a noncanonical form of RNA synthesis in which a nucleotide specified by a single base in the DNA template is repetitively added to the nascent transcript. Here we determined the crystal structure of an RNA polymerase, the bacterial enzyme from Thermus thermophilus, engag...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Murakami, Katsuhiko S., Shin, Yeonoh, Turnbough, Charles L., Molodtsov, Vadim
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547606/
https://ncbi.nlm.nih.gov/pubmed/28652344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702741114
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